Patients with clinically isolated syndrome optic neuritis (ON-CIS) perform worse in visually dependent cognitive tests than visually non-dependent tests.
Why this matters
Clinically isolated syndrome (CIS) is one of the disease courses of multiple sclerosis (MS) and cognitive assessments have been used to determine a patient’s risk for developing MS.
Patients with CIS often present with optic neuritis (ON), which may impact cognitive assessments results, particularly those that have a visual component.
An assessment of patients with ON-CIS is important to determine the influence of visual impairment on cognitive function.