VPS13C variants in late onset Parkinson’s disease

Takeaway

  • In a large cohort of participants with late onset Parkinson’s disease (LOPD), there was not frequent heterozygous or biallelic VPS13C variants.

Why this matters

    While VPS13C mutations have been identified as causative for early-onset PD, the rarity of VPS13C variants in LOPD indicates that they play a limited role in development of LOPD.