Walking performance in those with MS is related to physical activity and peak oxygen consumption


  • Walking performance is better in those with multiple sclerosis (MS), who have both higher levels of physical activity and peak oxygen consumption (VO2peak).

  • Higher VO2peak alone was not seen to improve walking outcomes; moderate-to-vigorous physical activity (MVPA) alone may improve walking outcomes.

Why this matters

  • In those living with MS, a chronic inflammatory disease, a decline is seen in both physical activity and VO2peak over time. These are thought to contribute to poorer walking performance.

  • Any strategies to improve this declining walking performance are eagerly sought by the 2.3 million people living with MS globally.