What can tract-based spatial statistics reveal in cervical spondylosis patients with pain?


  • Tract-based spatial statistics (TBSS) can be used to detect white matter alterations and their associations with pain intensity in patients with cervical spondylosis (CS).

Why this matters

  • People with cervical spondylosis (CS) can experience neck and shoulder pain, problems with gait and hand coordination, and emotional disturbance.

  • Findings of spinal imaging in CS are not always consistent with clinical symptoms scores, therefore, it is important to consider the whole nervous system when assessing a patient with CS.

  • TBSS is a method widely used to identify white matter alterations in several other conditions and the findings of this study suggest that it may also be used for evaluation of the pathophysiological characteristics in CS patients with pain.