Which genetic test is the most cost-effective in the diagnosis of unexplained epilepsy?

Takeaway

  • Whole-exome sequencing (WES) and epilepsy panel (EP) genetic tests are the most cost-effective genetic tests for epilepsy with an unknown etiology.

Why this matters

  • Cost-effectiveness analyses support the use of WES and EP genetic tests in the diagnosis of unexplained epilepsy, but do not support the use of chromosomal microarray (CMA).