Whole-brain cerebrovascular reactivity as an imaging biomarker of cognitive impairment

Takeaway

  • Whole-brain cerebrovascular reactivity was lower in people with cognitive impairment than a group of normal people and was associated with cognitive performance independent of Alzheimer’s disease (AD) pathology.

Why this matters

    Whole-brain cerebrovascular reactivity from hypercapnia-MRI may be a useful biomarker for assessment of cognitive impairment in older individuals.